Dynamic Contrast-Enhanced MRI to Study Atherosclerotic Plaque Microvasculature
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منابع مشابه
Dynamic Contrast-Enhanced MRI to Study Atherosclerotic Plaque Microvasculature
Rupture of a vulnerable atherosclerotic plaque of the carotid artery is an important underlying cause of clinical ischemic events, such as stroke. Abundant microvasculature has been identified as an important aspect contributing to plaque vulnerability. Plaque microvasculature can be studied non-invasively with dynamic contrast-enhanced (DCE-)MRI in animals and patients. In recent years, severa...
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BACKGROUND AND PURPOSE Intracranial atherosclerotic disease plaque hyperintensity and/or gadolinium contrast enhancement have been studied as imaging biomarkers of acutely symptomatic ischemic presentations using single static MR imaging measurements. However, the value in modeling the dynamics of intracranial plaque permeability has yet to be evaluated. The purpose of this study was to use dyn...
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Introduction Inflammation plays an important role in both atherosclerotic plaque progression and rupture [1], which has led to an interest in treatments with anti-inflammatory effects. To assess and monitor inflammation in vivo, dynamic contrast-enhanced (DCE) MRI has been previously demonstrated [2]. Kinetic parameters derived from DCE-MRI, including the transfer constant (K) and partial plasm...
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ژورنال
عنوان ژورنال: Current Atherosclerosis Reports
سال: 2016
ISSN: 1523-3804,1534-6242
DOI: 10.1007/s11883-016-0583-4